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KMID : 1103920130190030305
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Korean Journal of Hepatology
2013 Volume.19 No. 3 p.305 ~ p.308
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Co-development of autoimmune hepatitis and Sjogren’s syndrome triggered by the administration of herbal medicines
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Oh Hyo-Jeong
Mok Young-Mi
Baek Moon-Seong
Lee Ji-Kyeong
Seo Bong-Soo
Kim Tae-Hyeon
Choi Keum-Ha
Hwang In-Kyeom
Ra Ji-Eun
Oh Yong-Reol
Kim Yong-Sung
Cho Eun-Young
Kim Haak-Cheol
Sohn Young-Woo
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Abstract
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Autoimmune hepatitis (AIH) has been reported in association with Sjogren’s syndrome (SS). Drug-induced AIH has been rarely reported. A rare case of the co-development of AIH and SS in a 53-year-old woman after the consumption of herbal medicines is described. After admission, the patient complained of dryness in her mouth, and she was subsequently diagnosed with SS, which had not been detected previously. The patient’s bilirubin and aminotransferase levels initially decreased following conservative management; however, they later began to progressively increase. A diagnosis of AIH was made based on the scoring system proposed by the International Autoimmune Hepatitis Group. The patient was administered a combination of prednisolone and azathioprine, and the results of follow-up liver-function tests were found to be within the normal range. This is an unusual case of AIH and SS triggered simultaneously by the administration of herbal medicines.
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KEYWORD
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Autoimmune hepatitis, Sjogren’s syndrome, Herbal medicine
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